P160 Striking the balance between cystic fibrosis and Cystic Fibrosis-Related Diabetes (CFRD) - a meta-ethnography

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Cystic fibrosis related diabetes.

Diabetes is a frequent complication seen in cystic fibrosis patients as they reach adulthood. Cystic fibrosis related diabetes (CFRD) is distinguished as a separate entity with features that include progressive loss of islet beta cell mass and insulin deficiency, as well as insulin resistance. Abnormalities in glucose tolerance may be detectable for many years prior to the development of overt ...

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Cystic Fibrosis Related Diabetes

Diabetes mellitus and glucose intolerance are common in adolescent and adult patients with CF (Lanng et al, 1995; Moran et al, 1998). The prevalence of CF related diabetes (CFRD) increases with age (Moran et al, 1998) and in patients over 20 years of age may be as high as 53% (Lanng et al, 1995). CFRD occurs in up to 30% of individuals by the age of 25 and is invariably associated with pancreat...

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Cystic Fibrosis-Related Diabetes

Cystic fibrosis (CF) is the most common autosomal recessive disorder in Caucasian populations. Individuals with CF have seen significant increases in life expectancy in the last 60 years. As a result, previously rare complications are now coming to light. The most common of these is cystic fibrosis-related diabetes (CFRD), which affects 40-50% of CF adults. CFRD significantly impacts the pulmon...

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The use of fructosamine in cystic fibrosis-related diabetes (CFRD) screening.

OBJECTIVE To determine whether serum fructosamine correlates with glycemic control and clinical outcomes in patients being screened for cystic fibrosis-related diabetes (CFRD). METHODS Fructosamine and percent predicted forced expiratory volume in 1s (FEV1) were measured in patients undergoing a 2h oral glucose tolerance test (OGTT) for CFRD screening. Fractional serum fructosamine (FSF) was ...

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Cystic fibrosis-related diabetes: a distinct condition.

Cystic fibrosis is the most common fatal inherited autosomal recessive disease in Caucasians, affecting approximately one out of every 2,000 births. Survival of patients with cystic fibrosis has significantly improved due to advances in respiratory and nutritional care, and their current average life expectancy is 30-40 years. Development of cystic fibrosis-related diabetes is a comorbidity tha...

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2018

ISSN: 1569-1993

DOI: 10.1016/s1569-1993(18)30455-7